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Focus on Safety:
Biomechanical Impacts on Sterilized Allograft Bio-implants
A number of studies have been conducted regarding the effects of sterilization on bio-implants. For example, studies have shown that uncontrolled gamma irradiation of freeze-dried or hydrated samples at room temperature negatively affects biomechanical tissue properties. In contrast, irradiated deep-frozen bone allografts seem to be less brittle than similar grafts irradiated at room temperature. Tissue banks have incorporated this finding into the development of improved sterilization methods for allograft tissue and now carry out sterilization at low temperatures.
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Focus on Quality:
Donor Age Criteria: Are Allografts From Younger Donors Better?

Allograft tissues have been used for clinical sports medicine applications since the mid-1980s. Human allograft tissue offers several distinct advantages over autografts including shorter operative times, reduced surgical morbidity, decreased post-operative pain and improved cosmesis. As a result, musculoskeletal allograft tissue is increasingly being used for orthopedic applications. Allografts for sports medicine applications are recovered from a variety of sites and include mainly the patellar tendon, the semitendinosus tendon, the tibialis tendon (both anterior and posterior), the peroneus longus tendon, the gracilis tendon and the Achilles tendon.
Results of recent studies evaluating the effect of donor age on the mechanical properties of soft tissue bio-implants suggest that the use of tissue from donors up to age 70 is justified for ACL and PCL reconstruction. In fact, you may be surprised to learn that clinical studies have found no significant correlation between donor age and the mechanical properties of allograft tissue.
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Focus on Service:
Cranial Bone Flap Processing Continuing Education Program Offered
LifeNet Health, in affiliation with Pfiedler Enterprises, now offers a Continuing Education Program (1 credit) for perioperative nurses, surgical technologists, and other health care professionals who are interested in learning more about the clinical implications and applicable regulations regarding processing of autologous cranial bone flaps in the hospital setting versus outsourcing to an accredited tissue bank.
Every year in the United States, approximately 30,000 people suffer traumatic brain injuries that require the removal of a cranial bone flap, a life-saving procedure to relieve the pressure of brain swelling. In the operating room (OR) at the time the cranial bone flap is removed, there are several options for handling it.
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Focus on Innovation:
Ambient Temperature Storage Technology Saves Time
and Bio-Implant Integrity
Preservon® is an allograft bio-implant preservation technology available only through LifeNet Health. Preservon represents a huge leap forward in the ease, convenience and time associated with storing, shipping and implanting allografts. That’s because Preservon allows you to store bio-implants at ambient room temperature. Gone are the delays associated with thawing and re-hydrating your bio-implants. Preservon also greatly reduces the potential for brittle product.
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